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To make this easier, the research group of the University of Maryland has proposed the use of the AP s neighborhood graph map (Arbaugh nd; Mishra et al 2003a,c) The neighborhood graph is an approximate AP location graph map representing a mobility path between APs This map is constructed on the basis of the AP MAC address that is sent from the new AP when the STA moves from a current associated AP to a new associated AP Mishra (Mishra et al 2003c) proposes three methods for key distribution to authenticate STA On the basis of the AP s neighborhood graph, these methods are improved and the target APs are clearer These methods are: Static roam keys: The AS pushes a unique seed for encryption key derivation (such as a pairwise master key or PMK) to each AP.

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Human Resources Educational Services Support Services Product Marketing Product Engineering Value Chain CGO receives input from all links in the product value chain, as well as from the international units that distribute those products. Regional or Country Unit Management

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Over the past 50 years, evidence has accumulated about the clinical signi cance of marked individual differences in metabolism of drugs and in responses to drugs at the sites of therapeutic and adverse actions. The pioneers Kalow and Lehman identi ed speci c inherited traits that produced these marked differences in people who were entirely normal unless challenged with the particular drugs (Motulsky, 1957; Kalow, 1962). This new area of investigation was named pharmacogenetics by Vogel (1959). That term has powerful meaning today, generally referring to the actions of particular, individual genes or a few speci c interacting genes on drug response or adverse drug reaction. Pharmacogenetics is a subclass of the eld eco-genetics, with drugs being one of the many environmental agents interacting with genetic (and nongenetic) variation in the host individual of various exposed populations (Omenn and Motulsky, 1978; Eaton et al., 1999). Eco-genetics, in turn, is a signi cant part of public health genetics (Khoury et al., 2000; Omenn, 2000a). The newer term pharmacogenomics should be reserved, we believe, for genomic analyses employing the powerful tools of modern molecular biology: comparative genome hybridization for ampli cation of gene copy number, gene expression microarray analysis of levels of hundreds or thousands of messenger RNAs, and proteomic analysis of the level of expression of very large numbers of proteins. These analyses aim to detect evidence of variation in response to pharmaceutical action and in host factors in uencing the absorption, distribution, metabolism, and excretion (ADME) of those chemical agents. Originally, these methods identi ed mostly spots of unknown function; now more mRNAs and proteins are identi ed with particular classes of genes or proteins and their known or likely functions. It is possible that automation of the new techniques will so facilitate testing and

31 DOCUMENT/VIEW ARCHITECTURE USING WIZARD The previous chapter discusses the non-Wizard solution to creating three Windows applications This approach is good as it provides a solution with very few lines of code However, the approach may be difficult for a beginning programmer who is burdened with the task of understanding Windows deeply before developing an application It is also not easy for the programmer to produce a professional-quality program if extensive use of Windows resources is required A professional-looking application requires the document/view application The document/view architecture is a program development approach that integrates documents that hold the data and present this data as an output using the view facility in MFC The approach involves the use of several classes in MFC and each one of them has access to several functions for utilizing the Windows resources.

When developing a system, it is very dif cult for developers to remove themselves from the process of building software to see how a user would actually interact with the software. Therefore, the best way to get feedback about a user interface is to show potential users the interface prototypes and evaluate their responses. For interfaces with few screens, it may only be necessary to give a user some paper prototype sketches of the screens. For large systems with many screens, it is better to give the user an interface prototype that they can click through to see how the system works. The user should interact with the interface without prompting from the developers, but the developers should ask the user questions as she uses the prototype. Observing the user will help to determine interface effectiveness. Additionally, the user should be able to document her experience as she uses the program and should ll out a questionnaire when she is nished using

The encryption key is then derived via some form of handshake One disadvantage of this scheme is that the past communication.

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